Lipodystrophy

Opening Statement
"This 17 year old girl presented to endocrine clinic with a history of polyuria and polydypsia. Please look at her and proceed."

This young girl who is short for her age has masculine facial appearance caused by loss of fat in the face. She has prominent muscles and inframazillary dimples.She also has loss of fat (fat atrophy) in the arms and hands, giving her a muscular appearance.

The diagnosis is partial lipodystrophy.

As the opening statement says she has polyuria and polydyspia, I would like to do a urine dipstick for sugar as this condition is associated with diabetes

Questions you may be asked
(1) What other conditions may be associated with lipodystrophy apart from diabetes
**HIV on antiretroviral therapy
**Mesangiocapillary glomerulonephritis
**Localized scleorderma
**Morphea
**Chronic replasing panniculitis

Contributed by Giant Eagle